Non – IAPA IAPA p-value
n = 141 (89.2%) n = 17 (10.8%)
Age (years, median, (IQR)) 65 (50 - 73) 58 (56 - 63) 0.24
SAPS II score (median, (IQR)) 43 (32 - 63) 57 (35 - 59) 0.39
Female sex, n (%) 65 (46) 6 (35) 0.45
Influenza type A, n (%) 92 (65) 12 (71) 0.54
COPD, n (%) 43 (31) 4 (24) 0.53
Asthma (%) 5 (4) 3 (18) 0.05
Solid organ transplant, n (%) 1 (1) 1 (6) 0.68
Haematologic malignancy, n (%) 14 (10) 1 (6) 1.0
Lymphopenia*, n (%) 84 (60) 13 (78) 0.20
Neutropenia*, n (%) 3 (3) 1 (6) 0.44
Diabetes mellitus, n (%) 28 (21) 5 (30) 0.37
Cardiovascular disease, n (%) 54 (38) 7 (41) 0.80
Obesity, n (%) 24 (17) 0 0.07
Renal failure, n (%) 40 (28) 7 (41) 0.28
Corticosteroid before influenza diagnosis, n (%) 27 (19) 4 (24) 0.75
Immunosuppressive treatment before influenza diagnosis, n (%) 22 (16) 3 (18) 0.73
Antibiotics with ICU entry 63 (45) 7 (41) 0.78