5 Conclusions
In summary, this study provides the evidence that extreme environments changed the A/B compartments, reorganized the TADs and TAD boundaries of chicken 3D genome architectures. Moreover, Tight junction, Notch signaling pathway, Vascular smooth muscle contraction, RIG-I-like receptor signaling pathway and Glycosphingolipid biosynthesis pathways were suggested participating in extreme environment adaption.
Acknowledgements
This work was supported by the Jiangsu Provincial Key Laboratory of Poultry Genetics & Breeding (JQLAB-ZZ-202006).
Credit Author statements
Dan Shao : software, investigation, formal analysis, writing—Original draft /Reviewing & Editing. Yu Yang:conceptualization, methodology, writing—review and editing, supervision. Shourong Shi: conceptualization, investigation, writing—review and editing. Haibing Tong: validation, data curation. All authors read and approved the final version of the manuscript.
Data availability
The accession numbers for Hi-C data and transcriptome data reported in this paper are NCBI SRA (PRJNA817871) and SRA (PRJNA800119), respectively.
Competing interests
The authors declare that they have no competing interests.