2.5 Generation of interchromosomal contacts matrix
The expected number of
interchromosomal interactions for each chromosome pair i,j was
computed by multiplying the fraction of interchromosomal reads
containing i with the fraction of interchromosomal reads
containing j and multiplying by the total number of interchromosomal
reads. The enrichment was computed by taking the actual number of
interactions observed between i and j and dividing it by the expected
value.
The interchromosomal contact possibility was computed by the observed
reads pairs numbers between chromosome pair i,j dividing it by
its expected value. The expected number of interchromosomal interactions
for each chromosome pair i,j was calculated by multiplying the
proportion of interchromosomal reads containing i with the
proportion of interchromosomal reads containing j and the total number
of interchromosomal reads.