2.5 Generation of interchromosomal contacts matrix
The expected number of interchromosomal interactions for each chromosome pair i,j was computed by multiplying the fraction of interchromosomal reads containing i with the fraction of interchromosomal reads containing j and multiplying by the total number of interchromosomal reads. The enrichment was computed by taking the actual number of interactions observed between i and j and dividing it by the expected value.
The interchromosomal contact possibility was computed by the observed reads pairs numbers between chromosome pair i,j dividing it by its expected value. The expected number of interchromosomal interactions for each chromosome pair i,j was calculated by multiplying the proportion of interchromosomal reads containing i with the proportion of interchromosomal reads containing j and the total number of interchromosomal reads.