5 Conclusions
In summary, this study provides the evidence that extreme environments
changed the A/B compartments, reorganized the TADs and TAD boundaries of
chicken 3D genome architectures. Moreover, Tight junction, Notch
signaling pathway, Vascular smooth muscle contraction, RIG-I-like
receptor signaling pathway and Glycosphingolipid biosynthesis pathways
were suggested participating in extreme environment adaption.
Acknowledgements
This work was supported by the Jiangsu Provincial Key Laboratory of
Poultry Genetics & Breeding (JQLAB-ZZ-202006).
Credit Author statements
Dan Shao : software, investigation, formal analysis,
writing—Original draft /Reviewing & Editing. Yu Yang:conceptualization, methodology, writing—review and editing,
supervision. Shourong Shi: conceptualization, investigation,
writing—review and editing. Haibing Tong: validation, data
curation. All authors read and approved the final version of the
manuscript.
Data availability
The accession numbers for Hi-C data and transcriptome data reported in
this paper are NCBI SRA (PRJNA817871) and SRA (PRJNA800119),
respectively.
Competing interests
The authors declare that they have no competing interests.