Fig. 1. Plasma native thiol, total thiol, and disulfide bonds levels in preoperative and postoperative CPB (respectively, p <0.001, p <0.001, and p=0.001)
There was no statistical difference between preop and postop in terms of reduced thiol, oxidized thiol and thiol oxidation-reduction (p > 0.05 for all). Table 3 shows the thiol/disulfide parameters, IMA and albumin levels in the pericardial fluid. There was a negative correlation between pericardial fluid IMA and thiol/disulfide parameters (IMA vs. native thiol, r = -0.530, p < 0.001; IMA vs. total thiol, r = -0.552, p < 0.001; IMA vs. disulfide, r = -0.517, p < 0.001). (Fig 2).
Table 3. Pericardial fluid thiol/disulfide homeostasis in patients having CPB surgerya