REFERENCES:
- Martin PJ. How I treat steroid-refractory acute graft-versus-host
disease. Blood. 2020 May 7;135(19):1630-1638.
- McDonald GB. How I treat acute graft-versus-host disease of the
gastrointestinal tract and the liver. Blood. 2016 Mar
24;127(12):1544-1550.
- Penack O, Marchetti M, Ruutu T, Aljurf M, Bacigalupo A, Bonifazi F,
Ciceri F, Cornelissen J, Malladi R, Duarte RF, Giebel S, Greinix H,
Holler E, Lawitschka A, Mielke S, Mohty M, Arat M, Nagler A, Passweg
J, Schoemans H, Socié G, Solano C, Vrhovac R, Zeiser R, Kröger N,
Basak GW. Prophylaxis and management of graft versus host disease
after stem-cell transplantation for haematological malignancies:
updated consensus recommendations of the European Society for Blood
and Marrow Transplantation. Lancet Haematol . 2020
Feb;7(2):e157-e167.
- Tawara I, Sun Y, Lewis EC, Toubai T, Evers R, Nieves E, Azam T,
Dinarello CA, Reddy P. Alpha-1-antitrypsin monotherapy reduces
graft-versus-host disease after experimental allogeneic bone marrow
transplantation. Proc Natl Acad Sci U S A . 2012 Jan
10;109(2):564-569.
- Marcondes AM, Karoopongse E, Lesnikova M, Margineantu D, Welte T,
Dinarello CA, Hockenbery D, Janciauskiene S, Deeg HJ. α-1-Antitrypsin
(AAT)-modified donor cells suppress GVHD but enhance the GVL effect: a
role for mitochondrial bioenergetics. Blood . 2014 Oct
30;124(18):2881-2891.
- Marcondes AM, Hockenbery D, Lesnikova M, Dinarello CA, Woolfrey A,
Gernsheimer T, Loghman-Adham M, Gelmont D, Storer B, Hansen JA, Deeg
HJ. Response of Steroid-Refractory Acute GVHD to α1-Antitrypsin.Biol Blood Marrow Transplant . 2016 Sep;22(9):1596-1601.
- Magenau JM, Goldstein SC, Peltier D, Soiffer RJ, Braun T, Pawarode A,
Riwes MM, Kennel M, Antin JH, Cutler CS, Ho VT, Alyea EP 3rd, Parkin
BL, Yanik GA, Choi SW, Lewis EC, Dinarello CA, Koreth J, Reddy P.
α1-Antitrypsin infusion for treatment of
steroid-resistant acute graft-versus-host disease. Blood . 2018
Mar 22;131(12):1372-1379.
- Jerkins JH, Hamadani M, Zook F, Epperla N, Shaw BE, Saber W, Rizzo JD,
Pasquini M, Chhabra S, Drobyski WR, Hari PN, Shah NN.
Alpha-1-antitrypsin for the treatment of steroid-refractory acute
gastrointestinal graft-versus-host disease. Am J Hematol . 2017
Oct;92(10):E610-E611.
- Giannoni L, Morin F, Robin M, Peyneau M, Schlageter MH, Desmier D,
Pagliuca S, Sutra Del Galy A, Sicre de Fontbrune F, Xhaard A, Dhedin
N, Moins-Teisserenc H, Peffault de Latour R, Socié G, Michonneau D.
Human-Derived α1-Antitrypsin is Still Efficacious in Heavily
Pretreated Patients with Steroid-Resistant Gastrointestinal
Graft-versus-Host Disease. Biol Blood Marrow Transplant . 2020
Sep;26(9):1620-1626.
- Gergoudis SC, DeFilipp Z, Özbek U, Sandhu KS, Etra AM, Choe HK, Kitko
CL, Ayuk F, Aziz M, Baez J, Ben-David K, Bunworasate U, Gandhi I,
Hexner EO, Hogan WJ, Holler E, Kasikis S, Kowalyk SM, Lin JY, Merli P,
Morales G, Nakamura R, Reshef R, Rösler W, Srinagesh H, Young R, Chen
YB, Ferrara JLM, Levine JE. Biomarker-guided preemption of
steroid-refractory graft-versus-host disease with α-1-antitrypsin.Blood Adv . 2020 Dec 22;4(24):6098-6105.
- Glucksberg H, Storb R, Fefer A, et al. Clinical manifestations of
graft-versus-host disease in human recipients of marrow from
HL-A-matched sibling donors. Transplantation . 1974;18:295–304.
- Ganetsky
A
, Frey
NV , Hexner EO
, Loren
AW
, Gill
SI
, Luger
SM
, Mangan
JK
, Martin
ME , Babushok DV , Drobyski WR
, Smith
J , Timlin C , Freyer CW , Stadtmauer EA
, Porter
DL. Tocilizumab for the treatment of severe
steroid-refractory acute graft-versus-host disease of the lower
gastrointestinal tract. Bone Marrow Transplant . 2019
Feb;54(2):212-217 , Epub 2018 May 24.
- Roddy
JV , Haverkos BM
, McBride
A , Leininger KM , Jaglowski S
, Penza
S , Klisovic R
, Blum
W, Vasu S
, Hofmeister
CC
, Benson
DM , Andritsos LA
, Devine
SM , Efebera YA. Tocilizumab for steroid
refractory acute graft-versus-host disease.Leuk
Lymphoma. 2016;57(1):81-5. Epub 2015 Jul 3.
- Haznedaroglu BZ, Haznedaroglu IC, Walker SL, et al. Ultrastructural
and morphological analyses of the in vitro and in vivo hemostatic
effects of Ankaferd Blood Stopper. Clin Appl Thromb Hemost2010;16(4):446–453.
- Zeiser R, Blazar BR. Acute Graft-versus-Host Disease - Biologic
Process, Prevention, and Therapy. N Engl J Med . 2017 Nov
30;377(22):2167-2179.
- Weisdorf SA, Salati LM, Longsdor JA, Ramsay MKC, Sharp HL.
Graft-versus-Host disease of the intestine: A protein-losing
enteropathy characterized by fecal a1-antitrypsin.Gastroenterology 1983: 85: 1076–1081.
- Hagen LE, Schechter T, Luk Y, Brodovitch A, Gassas A, Doyle JJ. High
alpha-1 antitrypsin clearance predicts severity of gut
graft-versus-host disease (GVHD) in children. Pediatr
Transplant . 2011 Sep;15(6):659-663.