Conclusion
This study demonstrated a small decline in the CIRs and ASIRs of GC in the Saudi population between 2004 and 2017. Riyadh, Najran, and the Eastern Region had the highest overall ASIRs of GC among male and female Saudis, whereas Jazan had the lowest rates for both sexes. From 2004 to 2017, the ratio of GC cases in male Saudis was double that of female Saudis. Further epidemiological studies are required to determine the potential risk factors for GC in Saudi Arabia.