CONCLUSIONS
Like classical AIH, Seronegative AIH is also a diagnosis of exclusion
but there can be a diagnostic dilemma due to a lack of serological
autoimmunity evidence. Henceforth, the clinician should always keep this
diagnosis in the list of differentials because diagnosing this condition
and starting steroid therapy early in the course can lead to a
substantial improvement in the liver pathology. Otherwise, the
progression of the liver pathology in the absence of therapy can be
detrimental, leading to stages requiring a liver transplant. The disease
can also be recurrent if proper therapy is not instituted. Our case
showed that the diagnosis can sometimes be made retrospectively if
biopsy cannot be done.