Figure 1 Detection of S1-specific IgG and IgA antibodies in
serum and BALF.
Mice were immunized twice by intratracheal (IT) administration of S1
combined with or without SF-10 at days 0 and 14. Another group of mice
were immunized by intramuscular (IM) injection of S1 at the same time
schedules. At two weeks after the last immunization, the levels of
S1-specific IgG in serum (A) and S-IgA in BALF (B) were measured by
ELISA. Data represent S1-specific antibody titer of individual mice
(open rhombus) and their geometric mean (solid squares) (n =
6 mice per group). Differences
between same times immunization groups were analyzed by the
non-parametric Mann–Whitney U-test.**P <0.01 vs S1-IM,††P <0.01 vs S1-IT.