Data collection and statistical analysis
Data on characteristics, including sex, age, smoking status, alcohol consumption, comorbidities, the results of acid-fast bacilli (AFB) smear and mycobacterial culture, laboratory results, anti-TB regimen, anti-TB drug related side effects, and the onset and management of AKI, were collected. The estimated glomerular filtration rate (eGFR) was calculated using the Modification of Diet in Renal Disease formula [19].
All data are expressed as the number (%), mean ± standard deviation, or median (interquartile range). Intergroup differences were determined using a t test or Mann–Whitney U test for continuous variables based on their normality, and the chi-square test or Fisher’s exact test was used for categorical variables, as appropriate. Time to AKI for each variable was compared using the Kaplan–Meier method with the log-rank test. All variables with a p value ≤0.1 in univariate analysis were subjected to a multivariate Cox proportional hazards regression analysis to compute the adjusted hazard ratios (HRs) and 95% confidence intervals (CIs). All analyses were conducted using the Statistical Package for the Social Sciences 24.0 ([SPSS]; SPSS Inc, Chicago, IL, USA). Statistical significance was set at p< 0.05.