Secondary Analyses
In secondary analysis examining respiratory cultures by specimen source, ARI diagnosis remained associated with overall organism isolation among both TA cultures and BAL cultures (Table 5(a) ). ARI remained not associated with P. aeruginosa or S. aureus isolation within both specimen source types. In subgroup analysis examining children with chronic P. aeruginosa isolation (115 cultures among 20 children), children had similar distribution of the most common organism species identified with and without ARI, with the exception ofM. catarrhalis (Appendix Figure 2 ). ARI remained associated with overall organism isolation in this subgroup of children with chronic P. aeruginosa (Table 5(b) ). In subgroup analysis excluding 417 cultures (11.7% of the total cohort) obtained from same-day bronchoscopy encounters with no diagnosis data (presumed surveillance cultures), ARI diagnosis remained associated with organism isolation (Table 5(c) ).