Author Country Study design Setting Intervention target Aim Population
McDonald 2022
Canada
Cluster RCT
Acute care
Clinician, patient
To evaluate the effect of an electronic deprescribing decision support tool on adverse drug events after hospital discharge among older adults with polypharmacy
6,633 participants ≥65 years, taking ≥5 regular medications for any conditions, including gabapentinoids prior to hospital admission
Kasper 2014
Multiplea
RCT
Not reportedb
Patient
To evaluate the frequency and severity of discontinuation and rebound symptoms associated with pregabalin in patients with moderate-to-severe Generalised Anxiety Disorder
615 participants 18 to 65 years with a primary diagnosis of Generalised Anxiety Disorder
Chazot 2021c
United Kingdom
Observational
Primary care
Clinician, patient
To validate the efficacy of the Gabapentinoids and Opioids Tapering Toolbox (GOTT)
Clinicians who prescribe gabapentinoids (and opioid analgesics)
Collinson 2019c United Kingdom Observational Primary care Clinician To reduce gabapentinoid prescribing at the Haworth Medical Practice by 10% in one year Any patient prescribed regular gabapentinoids for any condition