Figure legends
Figure 1: sPLA2 inhibitory activity of the butanol soluble fraction of the aqueous extract of T. hispida (THB) in patients with acute dengue infection. The sPLA2 inhibitory activity was measured in patients with acute dengue (n=31), and the inhibitory activity of THB at a concentration of 0.1 µg/µL (THB C1) and 0.2 µg/µL (THB C2) was compared with a commercial sPLA2 inhibitor (CAY10590). The error bars represent the median and the inter quartile range.
Figure 2: Thin layer chromatography profile ofthe butanol soluble fraction of the aqueous extract of T. hispida (THB)
The TLC profile of THB was developed under the solvent system, ethyl acetate: methanol: water (8: 1.2:1 v/v/v). It was visualized as A- under 254 nm UV light, B- under 365 nm UV light and C- under 365 nm UV light after spraying with NPR/PEG reagent.
Figure 3: The HPLC chromatogram ofbutanol soluble fraction of the aqueous extract of T. hispida (THB)
The HPLC chromatogram of butanol soluble fraction of the aqueous extract of T. hispida (THB) was obtained along with the diode array UV spectra of the four major peaks, characterized as phenolics and flavonoids.