Figure legends
Figure 1: sPLA2 inhibitory activity of the butanol soluble
fraction of the aqueous extract of T. hispida (THB) in patients with
acute dengue infection. The sPLA2 inhibitory activity was measured in
patients with acute dengue (n=31), and the inhibitory activity of THB at
a concentration of 0.1 µg/µL (THB C1) and 0.2 µg/µL (THB C2) was
compared with a commercial sPLA2 inhibitor (CAY10590). The error bars
represent the median and the inter quartile range.
Figure 2: Thin layer chromatography profile ofthe butanol soluble
fraction of the aqueous extract of T. hispida (THB)
The TLC profile of THB was developed under the solvent system, ethyl
acetate: methanol: water (8: 1.2:1 v/v/v). It was visualized as A- under
254 nm UV light, B- under 365 nm UV light and C- under 365 nm UV light
after spraying with NPR/PEG reagent.
Figure 3: The HPLC chromatogram ofbutanol soluble fraction
of the aqueous extract of T. hispida (THB)
The HPLC chromatogram of butanol soluble fraction of the aqueous extract
of T. hispida (THB) was obtained along with the diode array UV
spectra of the four major peaks, characterized as phenolics and
flavonoids.