Strengths and Limitations
In the present study, in which data from an experienced tertiary center is presented, is valuable because the results of a particular clinical protocol are evaluated. However, the most important limitations of our study are its retrospective design and relatively low number of the patients among the group 2 and 4. Since the most common cause of pregnancy termination (75%) in the study was fetal structural anomalies, 63% of the patients were below the 24th gestational week. In addition, after second failured treatment, delivery with a another method other than LD vaginal misoprostol according to previous cesarean section history or cervical assessment may have affected the total length of hospital stay and time to delivery in all patient groups. However, considering that the high success rate with a single method is like 91% in our study, we believe that this is not an important variable.