Pd-Catalyzed Asymmetric Allylic C-H Functionalization Pu-Sheng Wang, Liu-Zhu Gong* Chin. J. Chem. 2023, 40, XXX—XXX. DOI: 10.1002/cjoc.202200XXX
This essay presents recent advances in Pd-catalyzed asymmetric allylic C-H functionalization in our lab, including the development of asymmetric catalytic systems, the mechanism of allylic C−H activation and the control of stereo- and regioselectivity. A diverse range of α-alkenes have been active allylic reagents to engage in the reactions to access synthetically useful building blocks, enabling the asymmetric synthesis of a range of natural products and biologically molecules.