3.3 Signal values associated with hepatic dysfunction at PT level
In the secondary outcomes for the high frequency reporting of hepatic dysfunction events associated with voriconazole, the RORs (95% CI) for hepatic function abnormal, cholestasis, alanine aminotransferase increased, blood alkaline phosphatase increased, aspartate aminotransferase increased, liver function test abnormal, gamma-glutamyl transferase increased, liver disorder, hepatocellular injury, blood bilirubin increased were 19.17 ( 95% CI 15.54-23.63), 37.03 ( 95% CI 29.95-45.78 ), 8.59 ( 95% CI 6.71-11.00 ), 21.96 ( 95% CI 17.14-28.13 ), 10.17 ( 95% CI 7.91-13.08 ), 17.10 ( 95% CI 13.27-22.04 ), 20.89 ( 95% CI 16.11-27.09 ), 9.23 (95% CI 7.02-12.14 ), 18.81 (95%CI 14.26-24.81 ), 13.32 (95% CI 9.92-17.88 ), respectively (Fig.3 ).