Primary outcome
Patients in group A had
significantly higher Hb levels
(108.4±11.4 g/L) than those in
groups B and C (107.8±8.4 and 103.9±8.8 g/L, respectively) on the day
after surgery, and the Hb level in group B was also higher than that in
group C (p=0.0202). However, on postoperative day 3, no significant
difference was found between groups B and C in Hb levels (97.4±10.5 and
93.5±10.8 g/L, respectively) (p=0.1192), even if the Hb level in group A
(102.2±10.9 g/L) was still markedly higher than that in groups B and C.
No difference was found among the three groups at other time points.
(Fig. 2).
In terms of blood loss, no significant difference was found in
intraoperative blood loss among groups A, B and C (88.6±19.5, 90.7±23.4,
and 87.2±22.6 ml, respectively) (p=0.679), but on postoperative day one,
the calculated blood loss was greater in groups B and C (378.9±123.1 and
436.4±147.4 ml, respectively) than in group A (313.4±118.5 ml)
(p<0.05), and group C had more blood loss than group B
(p=0.044). Regarding total blood loss, groups B and C had more total
blood loss (611.0±227.5 and 751.4±301.5 ml, respectively) than group A
(498.1±197.3 ml) (P<0.05), and group C had more blood loss
than group B (p<0.01) (Table 2). There was no report
allogeneic transfusion during the trial in any of the three groups.