Conclusions
A small dose of daily rhEPO from
preoperative day 5 to postoperative day 3 could significantly decrease
perioperative blood loss as well as slow the decline in postoperative Hb
levels in TKA patients without causing additional complications, which
was better than the dosing schedule from preoperative day 3 or from the
day of surgery. In summary, we recommend a more practical and highly
effective therapeutic plan of a small dose of daily subcutaneous rhEPO
from preoperative day 5 to postoperative day 3 in patients who have
undergone TKA.