Fig. 2 Genome duplication in Tiarella polyphylla . (A) Syntenic depth pattern between (a) T. polyphylla vs V. vinifera and (b) T. polyphylla vs C. japonicum . (B) Macrosynteny patterns showing that a typical region in T. polyphylla can be traced to no more than one region in V. vinifera and C. japonicum respectively. (C) Distribution of synonymous nucleotide substitutions (Ks ) among T. polyphylla , V. viniferaand C. japonicum .