Abstract
The occurrence of secondary renal cell carcinoma following
chemoradiotherapy for nephroblastoma is relatively rare, especially
microphthalmia transcription factor family translocation renal cell
carcinoma (RCC). A 13-year-old Japanese male was referred to our
department for treatment of a right kidney mass. The patient had
undergone open left nephrectomy and adjuvant chemotherapy for
nephroblastoma, 12 years before. Diagnostic imaging revealed a tumor in
the right kidney and a lesion suspected to be metastasis in the left
eighth rib. Partial nephrectomy by robot-assisted surgery for the right
renal tumor and resection of the left eighth rib were performed.
Pathologically, the renal tumor was diagnosed as translocation RCC, and
the rib lesion demonstrated no evidence of malignancy. In this study, we
present a rare case of secondary translocation RCC after successful
treatment of nephroblastoma.