3.4. Histopathological Examinations
In the H&E sections, there was normal heart histology in the control
group (Figure 3a). - In the
hearts of all rats in the other groups, contraction bands with necrosis
in focal areas, karyolysis characterized by the absence of nuclei in
myocytes, were interpreted as focal and histopathological changes
consistent with early stage myocardial infarction associated with
ischemia. The SALD and SAHD groups had more common and significant signs
of ischemic changes compared to the other groups. These changes were
observed to be compatible with 4-12 hours of ischemia. The wavy
appearance in myocytes was such that their cytoplasm contained
eosinophilia and contraction band (Figure 3b and 3c).