Study endpoints
The outcomes of each study are detailed in Supplemental Table 3. The main findings of the studies are summarised in Supplemental Tables 4.1, 5.1, 6.1, 7.1, 8.1 and 9.1. Visual inspection of the funnel plots for the main and secondary outcomes of interest as well as the non-statistically significant Egger’s test for each suggested the absence of publication bias in our study (Supplemental Figures 4.5, 5.5, 6.5, 7.5, 8.5 and 9.5).