Figure 2. Differential metabolic profiles of VVC vs CTL groups. (A) Principal component analysis (PCA) suggested that VVC has unique metabolic characteristics. (B) Statistical validation of permutation analysis (200 times) of PLS-DA models for VVC and CTL. (C) The permutation tests were performed based on LC-MS data from the VVC group and the CTL group. The intercept values of the regression line and the Y-axis were R2 and Q2, respectively.