Per TMP set-point a maximum of two representative experiments are
presented here.
A “>” preceding the logarithmic reduction factor (R)
combined with a “no” result for the parameter “virus breakthrough”
indicates removal below the limit of detection for all of the filtrate
fractions.
If minimal virus infectivity was found in a minority of the filtrate
fractions (i.e., the titers were at the limit of detection) then the
result for virus-breakthrough is “minimal”.
A “minor” virus breakthrough indicates that minimal infectivity was
found in the majority of the filtrate fractions.
Table 3. Filtration conditions and results for MMV retention –
2nd generation filter II (SG II) – ASAHI Planova
BioEX.