HIV‑1 drug resistance and subtype analysis
Antiretroviral resistance mutations and subtype analysis were identified
using the HIVdb program of the Stanford University HIV Drug Resistance
Database
(http://hivdb.stanford.edu;
version 9.1, Algorithm Date: 2 June 2022) 18. The sum
of the average resistance mutation scores in each patient’s HIV-1
polymerase (pol ) gene sequences, comprising protease, reverse
transcriptase, and integrase, was obtained from the Stanford HIV Drug
Resistance Database (HIVdb). The drug resistance intensity was
classified as S (susceptible, potential low-level resistance), I (low or
intermediate level resistance), or R (high-level resistance), based on
the Stanford HIVdb algorithm results.