IP-10 responses according to TST, QFT and microbiological tests
results
Assuming that Mtb.-infected children constitute a heterogenous group of
patients in terms of TST, QFT, and microbiological confirmation, we
compared children with different test results configuration for IP-10
expression. We found significant differences within LTBI group with
higher IP-10 levels in children with
TST+QFT+ LTBI than in those with
discordant TST and QFT results
(TST-QFT+ and
TST+QFT-; p = 0.009 and p
< 0.0001, respectively). No differences were observed between
children with discordance (p > 0.05). In ATB group, there
were no differences in IP-10 levels between children with and without
microbiological confirmation, or with and without positive culture
result (p = 0.79 and p = 0.53, respectively).