3 Materials and methods
3.1 Data source and
collection
We used data from the FAERS database published between January 2004 and
December 2021. Reports on adverse event and medication error in the
FAERS database was spontaneous reported by medical workers, consumers,
and manufacturers globally[22]. Each FAERS report contain patients
demographic information(age, gender and weight), drug
information(indication, dosage, and interval of administration), adverse
events information(occurrence time, outcome) and other
information(report year, report country and reporter occupations). In
the circumstances that there were multiple reports of the same event,
deduplicated procedure were perform in accordance with FDA
recommendation.