Maternal outcomes
Maternal outcomes are described in
Table 2 and Table 3. Analyses were
adjusted for maternal age, progestational BMI, ART pregnancy, operative
hysteroscopy, prior cervical surgery, prior sPTB, GA at diagnosis,
amniotic membrane prolapse, WBC, CRP at diagnosis. Compared with the
control group, median GA at
delivery was significantly higher (30.5 vs 27 weeks, Bate: 3.40, 95%
CI:2.13-4.67, p<0.001) and median pregnancy latency was
significantly longer (56 vs 28 days, Bate:24.04, 95% CI:13.31-34.78,
p<0.001) in the case group. McDonald-Shirodkar combined
technique was associated with significantly lower incidence of sPTB at
<28 weeks (16.7% vs 57.1%, aOR: 0.15, 95% CI: 0.05-0.44, p=
0.001), <30 weeks (38.1% vs 76.8%, aOR: 0.17, 95% CI:
0.06-0.48, p= 0.001), <32 weeks (54.8% vs 88.1%, aOR: 0.16,
95% CI: 0.05-0.50, p= 0.002), and <34 weeks (73.8% vs
92.9%, aOR: 0.22, 95% CI: 0.05-0.90, p= 0.036). The mode of delivery
and the rates of PPROM <34 weeks did not differ between the
two groups. The Kaplan–Meier curves in Figure 2 showed that the
cumulative percentage of patients with delayed birth was significantly
higher in case group than in the control group. The log-rank test showed
a significant increase in pregnancy prolongation (p < 0.001).