Figure 3 MR analysis results on the causal effects of serumSHBG levels on COVID-19 susceptibility and severity.
Panel A. Causal effects of serum SHBG levels on SARS-CoV-2 infection in men and women. Panel B. Causal effects of serum SHBG levels on COVID-19 hospitalization in men and women. Panel C. Causal effects of serum SHBG levels on COVID-19 critical illness in men and women. SHBG levels were measured in nmol/L and analyzed as a continuous phenotype.
Abbreviations: BMI, body mass index; CI, confidence interval; IV, instrumental variable; OR, odds ratio; SHBG, sex hormone binding globulin.