ALPM, anterior-lateral/posterior-medial diameter index; AP,
anterior–posterior diameter index; THi, tenting height index; PHi,
prolapse volume index; TVi, tenting volume index; PVi, prolapse volume
index; ACi, annular circumference index; AML, anterior mitral leaflet;
PML, posterior mitral leaflet
Figure 1 3D parametric models (D) of patient’s mitral valve by
MVN analysis. Three orthogonal mitral annulus images, including
two-chamber view (A), long-axis view (B) and short-axis view (C)were
displayed and subsequently used to model the entire annulus and mitral
valve.
Figure 2 A: Scatterplots demonstrating the distribution of
tenting volume index among healthy controls and MVP patients and the
cutoff value of 0.7 mL/m2 (horizontal dashed line) to
distinguish the occurrence of secondary leaflet tethering in MVP
patients. B to E: Histograms comparing the tenting volume index (B),
annular area index, prolapse volume index and AHCWR between the healthy
controls, MVPt- and MVP+ group.
Figure 3 Correlations of tenting volume index with NT-proBNP
and 3D VCA. The scatterplot demonstrates a mild correlation between
tenting volume index and NT-proBNP (A) and 3D VCA (B). C: ROC curve for
3D VCA to predict the occurrence of secondary leaflet tethering.
Figure 4 Illustrative examples of mitral valve prolapse
patients without and with secondary leaflet tethering. A mitral valve
prolapse patients without secondary leaflet tethering (PVi = 0.69
mL/m2, tenting volume index = 0.19
mL/m2, VCA = 0.32 cm2) B and C
mitral valve prolapse patients with secondary leaflet tethering and
larger regurgitant orifices. Case B PVi =0.02 mL/m2,
tenting volume index = 1.46 mL/m2, VCA = 0.95
cm2; Case C PVi = 0.25 mL/m2,
tenting volume index = 2.2 mL/m2, VCA = 1.48
cm2)