Simplified story
Many species are distributed across climatic gradients and are expected to adapt locally to climatic conditions such as temperature or precipitation. Here, we investigate genomic adaptations in a small mammal distributed throughout Europe (3,200 km) using a multivariate and multimethod approach, sampling 12 populations and 275 individuals. We found strong spatial structuring of populations, and identified candidate genes for climate adaptation. Signatures of environmental selection were associated with genes mainly related to energy homeostasis and pathogen response. Understanding local adaptation is important for our ability to predict species resilience to climate change.