Figure 1. In vitro characterization
and safety assessment of 68Ga-HZ20. (A) Schematic
illustration of the synthesis of the 68Ga-HZ20 probe.
(B) Radiolabeling rate (RLR) of 68Ga-HZ20 at different
temperatures. (C) Radiochemical yield of 68Ga-HZ20 at
different temperatures (n=3). (D) Stability analysis of68Ga-HZ20 over time in saline and 5% HSA at 37℃
(n=3). (E) HE staining of major organs indicates the safety of
radio-tracer (n=5). (F) IHC of ACE2 expression levels in major organs.