Figure 5. Evaluation of 68Ga-HZ20 in rhACE2-intraperitoneal spleen model. (A) PET imaging with in situinjection of different doses of rhACE2 in the spleen. The white box indicates the spleen injection site (K, B stands for kidney and bladder). (B) Comparison of SUVmax in the spleen in Figure 5A and Figure S8. (C) The ratio of spleen to muscle SUVmax. (D) ex vivo PET imaging of spleen tissue. (E) Comparison of spleen tissue % ID/g. (F) Correlation analysis between SUVmax and rhACE2 doses at 45 min after injection. (G) Western blot of rhACE2 at the injection site.