Figure 6. Evaluation of 68Ga-HZ20 in rhACE2- intraperitoneal brain model. (A) PET imaging with in situinjection of different doses of rhACE2 in the brain. The white circle indicates the brain injection site (K, B stands for kidney and bladder). (B) Comparison of SUVmax in the brain in Figure 6A and Figure S9. (C) The ratio of brain to muscle SUVmax. (D) ex vivo PET imaging of brain tissue (E) Comparison of brain tissue % ID/g. (F) Correlation analysis between SUVmax and rhACE2 doses at 30 min after injection. (G) Western blot of rhACE2 at the injection site.