Cutaneous metastases occur in approximately 0.7–0.9% of all cancer patients.¹ Cutaneous metastasis can cause symptoms such as exudates, bleeding, and pain, which remarkably reduce patient’s quality of life. Radiation therapy is one of the effective treatment methods for cutaneous metastasis.^2,3 Recently, the “Quad Shot” regimen, comprising 2 days of twice-daily fractionation with a fraction size of 3.5–3.7 Gy (14.0–14.8 Gy per cycle) repeated at 3–6-week intervals for a total of three cycles, has been successfully adapted for palliative treatment of head and neck cancer.^4,5 However, to the best of our knowledge, there is no reports of using the Quad Shot regimen for cutaneous metastasis.

Herein, we report a case in which radiation therapy using the Quad Shot regimen was effective in the treatment of cutaneous metastasis from parotid gland cancer.