Figure Legends
Figure 1.
PET-CT revealed FDG accumulated in the fundus of the gallbladder (SUV
max:4.2) (dotted arrow) and hepatoduodenal lymph nodes (SUVmax:3.2)
(solid arrow) as well as lymph nodes of the mediastinum.
Figure 2.
CT images (a) before chemotherapy and (b, c) after ten courses of
Nivolumab. After Nivolumab, the tumor had clearly shrunk (b, arrow), but
limited lymphadenopathy proximal to the abdominal aorta emerged (c,
arrow).
Figure 3.
NSE turned negative after ten courses of Nivolumab.
Figure 4.
There was a mass (15 x 8 x 10 mm) on the lower side of the gallbladder,
which was atrophied, with a thickened wall overall.
Figure 5.
NEC (solid arrow) and adenocarcinoma (in situ) components (dotted arrow)
were mixed (a). In the NEC component, the N/C ratio was increased, and
abnormal mitosis was observed (b). Furthermore, glandular duct structure
disappeared, and solid growth of NEC was observed (b). PD-L1 expression
is rarely seen (c).