Minimal stimulation IVF clinical outcomes compared to conventional IVF
We first and foremost want to the answer the question: whether minimal stimulation has the same efficacy in treating DOR related infertility.
In this study, 4,997 cycles of minimal stimulation IVF(MS-IVF) and 1,111 cycles of conventional stimulation(C-IVF) were included as comparison. We first compared the clinical outcomes in minimal stimulation and conventional IVF.
As shown in Table1, in patients diagnosed with DOR who met the study design and receiving IVF treatment, there was no differences in BMI, basal FSH levels, years of infertility as well as the percentage of primary infertility. However, there was significant differences in patients age, AMH level and AFC counts. Women of conventional IVF group were significantly younger, with higher AFC count and AMH level. This is congruent with our IVF strategy, women with “better” prognosis would always turn to conventional IVF in hopes of harvesting more available oocytes and embryos.
Table1. Basic Clinical characteristics of Conventional and minimal stimulation IVF