General patient information
In 16 years of clinical practice, between Jan 1st, 2005 and December 31st, 2021, more than 20,000 cycles of minimal stimulation IVF were done. Of which, a total of 14,139 of minimal stimulation IVF cycles that met the study design was eligible for inclusion. Of which, many cycles were the same patient undergoing a second or third IVF cycle or patients who turned to minimal stimulation after failed conventional stimulation cycles. These cycles were excluded for the purpose of statistical analysis. 6,108 cycles with the patients’ first time undergoing conventional IVF and minimal stimulation IVF were included in this study. Indeed, these women ovarian reserve were significantly poor, significantly worse than average IVF population.