Patients
In this study, women who had undergone minimal stimulation protocol in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI) in the Clinical Center of Reproductive Medicine, First Affiliated Hospital of Nanjing Medical University during January 1st, 2005 to December 31st, 2021 were considered for inclusion.
The inclusion criteria include: (1) women diagnosed with DOR (2) women age between 20 to 45 years of age. Exclusion criteria include: (1) PGD/PGS cycles (2) patients with chromosomal/genetic disorders or autoimmune diseases (3) patients with untreated severe endometriosis or intrauterine adhesion. For the propose of this study, women with the same inclusion and exclusion criteria who and undergone conventional ovarian stimulation protocol were also included.