Antibiotics
Jia et al.(Jia, Zhang et al. 2010) added different polyketide
antibiotics to the medium by A. terreus ATCC 20542, which leaded
to improve lovastatin titer by 20-25%, such as tylosin, erythromycin,
tetracycline, daunorubicin. Especially, lovastatin titer reached
952.7±24.3 mg/L at the initial stage of lovastatin synthesis with the
addition of 50 mg/L tylosin, increased by 42% and 22.2%, respectively.