HIF1α protein expression in rat liver tissue treated with DAS
and chalcone
The expression of HIF1α in tumor tissue was remarkably higher when
compared to their corresponding surrounding tissues which was noticed in
SULT1E1 expression. HIF-1 plays important roles in breast cancer
metastasis by mediating hypoxia-induced expression of mRNA-encoding
genes. HIF-1 also regulates the expression of non-coding RNAs, which are
critical regulators of migration, invasion, and metastasis (14).