HIF1α protein expression in rat liver tissue treated with DAS and chalcone
The expression of HIF1α in tumor tissue was remarkably higher when compared to their corresponding surrounding tissues which was noticed in SULT1E1 expression. HIF-1 plays important roles in breast cancer metastasis by mediating hypoxia-induced expression of mRNA-encoding genes. HIF-1 also regulates the expression of non-coding RNAs, which are critical regulators of migration, invasion, and metastasis (14).