Systemic Therapy Given, n (%) |
136 (85.5%) |
61 (95.3%) |
75
(79.0%) |
0.005 |
Primary Treatment Category, n (%)
Sirolimus
Vincristine
Siro+VCR
Steroids
Minimal
Surgery/IR
|
51 (32.1%)
25 (15.7%)
7 (4.4%)
32 (20.1%)
27 (17.0%)
17 (10.7%)
|
19 (29.7%)
16 (25.0%)
7 (10.9%)
16 (25.0%)
2 (3.1%)
4 (6.3%)
|
32 (33.7%)
9 (9.5%)
0 (0%)
16 (16.8%)
25 (26.3%)
13 (13.7%)
|
|
Time Between Initial Symptoms and Treatment Initiation (days), median
[IQR] |
52.0 [9.5, 235.5] |
16.0 [3.0, 44.0] |
179.0
[64.5, 456.0] |
<0.001 |
Time Between Diagnosis and Treatment Initiation (days), median [IQR] |
9.0 [1.0, 52.8] |
3.0 [1.0, 10.0] |
21.0 [6.0, 71.0] |
<0.001 |
Received Blood Product Transfusions, n (%) |
56 (35.2%) |
50 (78.1%) |
6 (6.3%) |
<0.001 |
Received Opioid Medication, n (%) |
33 (20.8%) |
19 (29.7%) |
14
(14.7%) |
0.028 |
Interventional Radiology Procedure Attempted, n (%) |
16 (10.1%) |
8
(12.5%) |
8 (8.4%) |
0.2 |
Surgical Resection Attempted, n (%) |
28 (17.6%) |
8 (12.5%) |
20
(21.1%) |
0.2 |
Reason for Treatment Initiation, n (%)
Coagulopathy
Thrombocytopenia
Anemia
Pain
Recurrent cellulitis
Visceral or bone involvement
Cardiac dysfunction
Airway compression
Limb dysfunction
Cosmetic look
Extent of disease
|
65 (40.9%)
59 (37.1%)
22 (13.8%)
61 (38.4%)
2 (1.3%)
12 (7.5%)
5 (3.1%)
11 (6.9%)
29 (18.2%)
34 (21.4%)
87 (54.7%)
|
51 (79.7%)
53 (82.8%)
21 (32.8%)
18 (28.1%)
1 (1.6%)
6 (9.4%)
5 (7.8%)
10 (15.6%)
9 (14.1%)
7 (10.9%)
40 (62.5%)
|
14 (14.7%)
6 (6.3%)
1 (1.1%)
43 (45.3%)
1 (1.1%)
6 (6.3%)
0 (0%)
1 (1.1%)
20 (21.1%)
27 (28.4%)
47 (49.5%)
|
<0.001
<0.001
<0.001
0.032
>0.9
0.5
0.010
<0.001
0.3
0.010
0.14
|