Treatment Group Treatment Group Treatment Group Treatment Group
Treatment Response
Sirolimus only (N=4) n (%) Siro + Steroids (N=15) n (%) VCR only (N=5) n (%) VCR + Steroids (N=19) n (%) p-value* (steroid groups only)
Any response at 3 months? 1/2 (50%) 11/12 (91.7%) 4/5 (80%) 17/17 (100%) 0.4
HemR at 3 months? 0 7/8 (87.5%) 3/3 (100%) 12/12 (100%) 0.4
RadR at 3 months? 0 2/3 (66.7%) 1/1 (100%) 5/7 (71.4%) >0.9
ClinR at 3 months? 1/2 (50%) 9/10 (90%) 3/4 (75%) 16/16 (100%) 0.4
Any response at 6 months 2/3 (66.7%) 13/14 (92.9%) 4/5 (80%) 17/17 (100%) 0.5
HemR at 6 months? 0 10/11 (90.9%) 3/3 (100%) 12/12 (100%) 0.5
RadR at 6 months? 1/2 (50%) 6/7 (85.7%) 3/3 (100%) 6/8 (75%) >0.9
ClinR at 6 months? 2/3 (66.7%) 12/13 (92.3%) 4/5 (80%) 16/16 (100%) 0.4