TABLE 2 Apixaban Dosing, Monitoring, and Peri-operative Management |
TABLE 2 Apixaban Dosing, Monitoring, and Peri-operative Management |
TABLE 2 Apixaban Dosing, Monitoring, and Peri-operative
Management |
Length of Apixaban Therapy Pre-Transplant (days) |
Length of Apixaban
Therapy Pre-Transplant (days) |
114.6 (38.5, 174.5)* |
Prophylaxis Indication (N%) |
Prophylaxis Indication (N%) |
68% |
Concomitant Aspirin use (N%) |
Concomitant Aspirin use (N%) |
21% |
Time from Last Dose to OR Arrival (hours) |
Time from Last Dose to OR
Arrival (hours) |
23.2 (17.2, 27.5)* |
Pre-OR Apixaban Level (ng/mL) |
Pre-OR Apixaban Level (ng/mL) |
37
(28.3, 59)* |
Time from Last Level to OR Arrival (hours) |
Time from Last Level to OR
Arrival (hours) |
6.2 (4.8, 8.4)* |
Chest Tube Out (mL/kg/hr) |
Chest Tube Out (mL/kg/hr) |
|
|
First 2 Post-Operative Hours |
1.9 (0.9, 5.9)* |
|
First 4 Post-Operative Hours |
1.8 (0.6, 4.5)* |
Patients Requiring Re-Operation for Bleeding (N%) |
Patients Requiring
Re-Operation for Bleeding (N%) |
5% |
Significant Post-Operative Bleeding (N%) |
Significant Post-Operative
Bleeding (N%) |
32% |
Operating Room, OR. *Median values with 25th and
75th interquartile range. |
Operating Room, OR.
*Median values with 25th and 75th
interquartile range. |
Operating Room, OR. *Median values with
25th and 75th interquartile
range. |