Author contributions
NDA, HA and NRE designed research. NDA, PAG, SAH, AP and NRE contributed analytical tools. DER, JFW, PA, FA, RA, SD, ARH, FSK, JMQ and JRR contributed samples. NDA analyzed data. NDA, PAG, DER, JFW, SAH, JMF, DB, ML, IF, NG, JR, HA and NRE interpreted data. NDA wrote the paper, with insightful contributions from all authors. All authors revised the manuscript and agreed with its publication.