Treatment of an adolescent with severe, refractory hemorrhagic cystitis
(HC). Despite aggressive treatment of HC with supportive care, cidofovir
when BK virus detected, ciprofloxacin, estrogen and 2 manual clot
evacuations with intravesicular cidofovir, he remained symptomatic with
significant pain, bleeding, and red cell transfusion dependent. After
treatment with human keratinocyte growth factor, his refractory HC
improved, and ultimately resolved.
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