3.5 Predictions of clinical outcomes
A total of 1550 PAH patients were included in logistic regression analyses after excluding the patients with concomitant use of PAH-specific vasodilators targeting the same biological pathways. Table 3 demonstrates the univariate and multivariate logistic regression models that estimate clinical outcomes (death or non-death) of the PAH patients reported in the JADER database. The multivariate model with the interaction term between epoprostenol and warfarin had lower AIC than without the interaction term. The area under the ROC curve of the final model was 0.668. Supplementary Table S3 summarizes the ORs of all variables in the univariate analyses.