Associations Between Sexual Type and HBV Infection
According to the questionnaire, sexual type was classified into nine groups, individuals with no sex (3.94%), heterosexual vaginal sex (10.23%), heterosexual oral sex (0.59%), heterosexual anal sex (0.04%), heterosexual multiple types (77.36%), bisexual sex (6.71%), male homosexual sex (0.74%), female homosexual sex (0.09%), and unclear (0.3%).
In comparison to participants without sexual behavior, we found that bisexual sex and male homosexual sex were found to be linked with an increased likelihood of contracting HBV infection. Specifically, in model 1, bisexual sex (OR=1.73, 95%CI: 1.15-2.59) and male homosexual sex (OR=4.82, 95%CI: 2.25-10.31) were identified as having a higher risk of HBV infection. In model 2, bisexual sex (OR=2.2, 95%CI: 1.44-3.36) and male homosexual sex (OR=6.58, 95%CI: 2.99-14.46) were correlated with an increased risk of HBV infection. Similarly, in model 3, bisexual sex (OR=1.69, 95%CI: 1.04-2.76) and male homosexual sex (OR=5.23, 95%CI: 1.95-13.99) were correlated with a higher risk of HBV infection. Conversely, there were no significant differences observed in heterosexual vaginal sex, heterosexual oral sex, heterosexual anal sex, or heterosexual multiple types across the three models.
Upon stratification by gender, in the men population, comparing with men without sexual behavior, heterosexual anal sex (OR=14.42, 95%CI: 3.66-56.81), bisexual sex (OR=4.32, 95%CI: 2.51-7.44) and male homosexual sex (OR=5.61, 95%CI: 2.53-12.48) exhibited an increased risk of HBV infection in model 1. Heterosexual anal sex (OR=4.75, 95%CI: 1.22-18.47), bisexual sex (OR=4.34, 95%CI: 2.43-7.77) and male homosexual sex (OR=7.75, 95%CI: 3.43-17.52) were found to be linked with an increased risk of HBV infection in model 2. Heterosexual anal sex (OR=4.52, 95%CI: 1.12-18.2), bisexual sex (OR=4.00, 95%CI: 2.09-7.64) and male homosexual sex (OR=5.65, 95%CI: 2.13-15) were found to be linked with an increased risk of HBV infection in model 3. No significant differences were observed in heterosexual vaginal sex, heterosexual oral sex, or heterosexual multiple types across all three models.
However, among the women population, compared with women without sexual behavior, whether heterosexual vaginal sex, heterosexual oral sex, heterosexual multiple types, bisexual sex, no statistically differences were observed across three models.