1. Introduction
Human cytomegalovirus (HCMV) is a double-stranded DNA virus belonging to the β-herpesviridae family 1. HCMV infection is common globally, with approximately 60% of people in developed countries having HCMV specific IgG antibodies, while in many developing countries this proportion exceeds 90% 2. This high prevalence rate of HCMV infection is mainly due to the fact that can be efected at any age through body fluids (i.e., urine, saliva, and human breast milk) from-infected individuals 3, and HCMV persists for the lifetime of the host after primary infection 4. HCMV infection in adults with normal immune function will not cause obvious clinical symptoms,however, primary infection usually occur in early childhood. A survey of HCMV infection found that HCMV seroprevalence reached 75% in children less than 6 years 5.
Due to the immature development of immune function of young children6, HCMV infection may cause diseases of liver, blood, digestive tract, kidney, lung and other organs 7-12, and young children have no specific clinical symptoms in the early stage of HCMV infection. Therefore, we need to investigate the hematology parameters (i.e., WBC, L%, LYM, ALT, AST, GGT, UREA, and CREA) of young children of different ages to provide a reference basis for diagnosis and treatment of infants infected with HCMV.