Inclusion and exclusion criteria are as follows:
Inclusion criteria: (1) HCMV-infected group:HCMV-DNA ≥ 4.0 ×
102 copies/ml in the urine of child, and the child has
not received antiviral treatment; (2) Control group
(no-HCMV-infected):HCMV-DNA < 4.0 ×
102copies/ml in the urine of children and diagnosed as
HCMV-infected.
Exclusion criteria: All subjects in this experiment should meet
the following exclusion criteria: (1) active or known chronic infection
(such as autoimmune disease, diabetes, and cardiovascular disease); (2)
infectious diseases (hepatitis virus, herpes virus, rubella virus,
rubella virus, mycoplasma, chlamydia, AIDS, syphilis, toxoplasma gondii,
and other infections); (3) serious blood disease; (4) history of
malignancy.