2.4 Statistical analyses
Statistical analysis was performed using the SPSS ver. 26.0 software (SPSS, Inc., Chicago, IL, USA). Quantitative data (such as WBC, L%, LYM, ALT, AST, GGT, UREA, CREA) with normal distribution or approximate normal distribution were expressed as mean ± standard deviation. T test or Mann-Whitney test was used to compare the data between the two groups. Comparing the data among multiple groups, the analysis of variance or Kruskal Wallis test is adopted. A P -value < 0.05 was considered to be statistically significant.