3.5 Hematological parameters of infants and children with HCMV infection in different age groups
There is no significant difference in white blood cells among different age groups except that L% and LYM in group 0-21d are slightly lower than those in group 22d-6m (P <0.05) (Table 5). In addition, HCMV infection in children of different ages can have different effects on liver function, among which the results of ALT in children aged 0d-21d are the lowest, however, infants of 22d-6m are the highest, and then decrease with the increase of children’s age (Table 5). AST of 22d-6m and 7m-11m groups was significantly higher than that in 0d-21d, 12m-23m, and 2y-6y groups (P <0.05) (Table 5). The GGT of HCMV-infected children aged 0d-21d was the highest, and then decreased with age (Table 5), which means that CMV may cause less hepatobiliary damage in older children in the 22d-6y age group. And children with 0-21d are special. Because the ALT of Infants aged 0d-21d is lower than other age groups, but GGT is significantly higher than other age groups, which suggests that the injuries of children aged 0d-21d may mainly come from gallbladder and bile duct. As for the effect of HCMV on renal function, UREA had no significant difference among different age groups, but CREA of 0d-21d group was significantly higher than that in other age groups(P <0.05) (Table 5). which indicating that children of 0d-21d age group may have a higher risk of kidney disease after being infected with HCMV.