1. Introduction
Human cytomegalovirus (HCMV) is a double-stranded DNA virus belonging to
the β-herpesviridae family 1. HCMV infection is common
globally, with approximately 60% of people in developed countries
having HCMV specific IgG antibodies, while in many developing countries
this proportion exceeds 90% 2. This high prevalence
rate of HCMV infection is mainly due to the fact that can be efected at
any age through body fluids (i.e., urine, saliva, and human breast milk)
from-infected individuals 3, and HCMV persists for the
lifetime of the host after primary infection 4. HCMV
infection in adults with normal immune function will not cause obvious
clinical symptoms,however, primary infection usually occur in early
childhood. A survey of HCMV infection found that HCMV seroprevalence
reached 75% in children less than 6 years 5.
Due to the immature development of immune function of young children6, HCMV infection may cause diseases of liver, blood,
digestive tract, kidney, lung and other organs 7-12,
and young children have no specific clinical symptoms in the early stage
of HCMV infection. Therefore, we need to investigate the hematology
parameters (i.e., WBC, L%, LYM, ALT, AST, GGT, UREA, and CREA) of young
children of different ages to provide a reference basis for diagnosis
and treatment of infants infected with HCMV.