3.2.2 Secondary indicators of inflammation
Icariin and its derivatives showed good therapeutic effects on the relevant secondary inflammatory indices, specific information is shown in the table (Table 4) . Among them, icariin and its derivatives can effectively inhibit the levels of IL-6 (p = 0.000), IFN-γ (p = 0.031) and TGF-β1 (p = 0.000), and at the same time significantly increase the levels of IkB-α (p = 0.000), NF-κB p65 (p = 0.000) and NLRP3 (p = 0.000), thereby achieving anti-inflammatory effects.