2.2.1 Research object and variable selection
The data source used in this study is the literature included in the Meta-analysis, and its inclusion and exclusion criteria are the same as those of the Meta-analysis. However, it is important to note that data from different studies with different sample sizes may introduce potential weighting factors leading to interfere with results in machine learning. We collected samples for all doses and durations in each literature. The relevant sample data of each document is interpolated with the average value of the corresponding index of the document. The sample data consisted of independent variables such as dose and treatment time. The dependent variable is a continuous variable, and we use TNF-α improvement rate ((Mean of control group-Mean of experimental group)/Mean of control group) as an index to evaluate the effectiveness of inflammation treatment.