3.2.2 Secondary indicators of inflammation
Icariin and its derivatives showed good therapeutic effects on the
relevant secondary inflammatory indices, specific information is shown
in the table (Table 4) . Among them, icariin and its derivatives
can effectively inhibit the levels of IL-6 (p = 0.000), IFN-γ
(p = 0.031) and TGF-β1 (p = 0.000), and at the same time
significantly increase the levels of IkB-α (p = 0.000), NF-κB p65
(p = 0.000) and NLRP3 (p = 0.000), thereby achieving
anti-inflammatory effects.