3.8 Cyanidin-3-O-glucoside
Anthocyanins are abundant natural water-soluble pigments, which are relatively rich in the skin of Glycine max (L.) Merr.. These compounds have been shown to exert antioxidant and anti-inflammatory properties (H. Zhang et al., 2020). Cyanidin-3-O-glucoside is one of the most abundant anthocyanins in nature. A study found that cyanidin-3-O-glucoside treatment not only suppresses blood lipids, but also improves endothelial cell function in a rabbit atherosclerotic model. Mechanistically, these effects are due to decreased expression of miR-204-5p, which leads to the increased expression of SIRT1 and enhanced endothelial cell function (Z. Wang et al., 2020).