a ) Pd PDH, polyol dehydrogenase fromParacoccus denitrificans ; b ) One unit is
defined as the amount of protein that produces or consumes 1 µM of
NAD(H)/NADP(H) per second; c ) n.a. = no
measurable activity.
Table 2. Kinetic parameters of Pd PDH mutants determined
with NAD+ or NADP+ using galactitol
as substrate in excess.