Comparisons of Characteristics and Outcomes between Eligible and Ineligible Patients, including those with CHADS2 score <2
The baseline characteristics of eligible and ineligible patients, including those with a CHADS2 score <2, are presented in Table 5 . By putting low-risk patients back into the ineligible group, it appears that there were more elderly patients and patients with comorbidities in the eligible group, contrary to what is shown in Table 3. Regarding outcomes, unlike the main analysis after excluding patients with CHADS2 score <2, there was no difference in stroke/SE risk between the groups, and the effect of ineligibility on the risk of major bleeding was smaller and did not reach statistical significance, although the risk of all-cause mortality remained significantly higher in ineligible patients with an unadjusted HR (95% CI) of 1.54 (1.29–1.83).