DOACs criteria Eligible n (%) Ineligible n (%)
Inclusion
Age age ≥18 years 7826 (100%)
AF non-valvular atrial fibrillation 7826 (100%)
CHADS2 CHADS2 score ≥ 2 5763 (73.6%) 2063 (26.4%)
Exclusion
Haemorrhage Risk History of major bleeding 7547 (96.5%) 279 (3.5%)
Uncontrolled hypertension
SBP > 180mmHg or DBP > 100mmHg
7701 (98.4%)
125 (1.6%)
Renal dysfunction Calculated CLCR < 30 mL/min 7085 (90.5%) 741 (9.5%)
Hepatic function ALT or AST > 2 times the ULN or TBL ≥ 1.5 times the ULN 7608 (97.2%) 218 (2.8%)
Haemoglobin & platelet count Hgb < 10 g/dL or platelet count < 100,000 cells/mL 7324 (93.6%) 502 (6.4%)
Antiplatelet therapy Aspirin > 100 mg daily or Aspirin in combination with thienopyridines 7550 (96.5%) 276 (3.5%)
Anti-inflammatory agents chronic treatment with NSAIDs 7513 (96%) 313 (4.0%)
Drug or alcohol dependence alcohol dependence 7783 (99.5%) 43 (0.5%)
Overall 4054 (51.8%) 3772 (48.2%)