Methods
S. aureus strains isolated from non-CRS controls (n=5), CRSsNP (n=4) and CRSwNP patients (n=4) were sequenced using short read paired sequencing and interrogated for carriage of virulence genes. A representative control and CRSwNP isolate were tested for intracellular survival in the LAD2 mast cell line to investigate phenotypic differences.