Author Contributions

Conception or design of the work: CXG, XMD and XQ; Acquisition,analysis,or interpretation of data: CXG,XMD and ZZ; Management and checking of all data: CXG, XMD, XQ, JZ, LJM and ZZ; Drafting the article: CXG. All authors critically reviewed the manuscript and interpreted the results. The final manuscript was read, checked and approved by all authors.