CONCLUSION
The present systematic review is of great interest in clinical and surgical medical practice because it presents the development of acute abdomen after vaccination against COVID-19. However, few studies related to this association have been reported, so they are infrequent and occur in the minority of vaccinated individuals. Despite this, patients responded adequately to treatment and no deaths related to these complications were reported. Importantly, the study involved a small sample of patients, and future observational studies are required. These studies could elucidate the various pathophysiological mechanisms by which this association occurs and provide more robust information on the safety of SARS-CoV-2 vaccines. Ultimately, the cases included and studied in this review indicate that cases are minimal upon administration of vaccination, so vaccines generally do not develop acute abdomen. However, despite this, physicians should monitor patients with a history or risk factors and observe the evolution of patients through clinical follow-up with a possible risk of developing these complications after any type of vaccination against COVID-19.