(2022)13
|
Female
69
|
None
|
Pfizer-BioNTech (mRNA)
|
Third
|
24 hours
|
Acute abdominal pain
|
BP: 96/61mm/Hg
HR: 107 beats/min
RR: 18 breaths/min
T: 36.7 °C
SpO2: 93%
|
RBC: 3.73 × 1012/L
Hb: 115 g/L
Hct: 34.8%
Neutrophils: 7.6 × 109/L
Cre: 1.17mg/dL
BUN: 21 mg/dL
|
CT:
Perforated acute appendicitis with appendicolith visualized at the base
of the appendix with associated mesenteric fat stranding, multiloculated
free fluid and trace free air
|
None
|
Acute appendicitis (perforated appendicitis)
|
Laparoscopic appendectomy converted by ileocecal resection
|
Recovered- Discharged at 6 days
|
|
Female
58
|
Left quadrantectomy with radiotherapy for breast cancer and
hypertension
|
Pfizer-BioNTech (mRNA)
|
First
|
2 days
|
Acute abdominal pain in the right iliac fossa
Fever
Nausea
Vomiting
|
The abdomen painful on deep palpation in RIF and hypogastrium
|
Hb: 125 g/L
WBC: 12.1 × 109/L
Neutrophils: 78.4%
Fibrinogen: 636.0 mg/dL
PT: 13.3 s
|
Ultrasound: fluid collection in the right inferior fossa and thickening
of the cecal wall.
CT: distended appendix with thickened walls.
|
Diffuse acute and chronic inflammatory infiltrates with scattered
non‐necrotizing granulomas throughout all layers of the appendiceal
wall
|
Acute appendicitis
|
Laparoscopic appendectomy
|
Recovered- Discharged at 4 days
|
Kawano et al.
(2022)22
|
Male
19
|
None
|
Modern (mRNA)
|
Second
|
28 days
|
Abdominal pain
Vomiting
Loss appetite
|
BP: 79/50 mmH
HR:
140 bpm
T:38.6°C
BMI: 16,3 kg/m 2
|
WBC :12.2 × 109/L
CRP: 10,27 mg/L
D-dimer: 1600 ug/L
hsTnT : 3.67 ng/mL
|
CT: swollen appendix
|
None
|
Acute appendicitis
Fulminant Myocarditis
|
Steroids and antibiotics
|
Recovered
|
Cieślewicz et al.
(2021)23
|
Female
29
|
None
|
Pfizer-BioNTech (mRNA)
|
First
|
20 h
|
Abdominal pain
|
T: 40°C
|
WBC: 13 × 109/L
%NEUT: 75.6 %
Urine amylase: 544 U/L
CRP: 128 mg/L
|
Abdominal USG: pancreas clearly visible in the head and body area not
enlarged, homogeneous
|
None
|
Pancreatitis acute
|
Fluid resuscitation, pain control, and nutritional support
|
Recovered- Discharged
|
Parkash et al. (2021)24
|
Female
96
|
Heart failure, hypertension, hypothyroidism
|
Pfizer-BioNTech (mRNA)
|
First
|
2 days
|
Epigastric pain radiating to the right lower chest
Nausea
|
No data
|
Amylase: 4036 U/L
|
CT:
No findings
|
None
|
Acute pancreatitis
|
Hydration, analgesics
|
Recovered
|
(2022)14
|
Male
82
|
Coronary artery disease, prostate cancer, proctocolitis complicated by
radiation
Hypothyroidism and gastroesophageal reflux disease
|
Pfizer-BioNTech (mRNA)
|
Third
|
Few hours
|
Epigastric abdominal pain acute with radiation to back
Nausea and two episodes of vomiting
|
Not found
|
Lipase: 2257 U/L
Triglyceride: 57 mg/dL
Calcium: 9.3 mg/dL
|
CT:
moderate peripancreatic fat stranding with tracking fluid into the
mesenteric root, suggestive for acute interstitial pancreatitis, without
evidence of necrosis
|
None
|
Acute pancreatitis
|
IV fluids, acetaminophen, hydromorphone, and metoclopramide
|
Recovered
|
(2022)25
|
Female
24
|
Pregnant (31 weeks of gestation)
|
Pfizer-BioNTech (mRNA)
|
First
|
1 week
|
Severe epigastric pain radiating
to the back
Nausea
Vomiting
|
BP: 140/90 mmHg
HR: 106 beats/min
RR:22 breaths/min
T: 39 °C
SpO2: 98%
|
WBC: 17 x 109/L
Lipase
4376 U/L
Amylase: 83 U/L
|
CT:
bulky pancreas with mild enhancement and marked peripancreatic fat
stranding with inflammation, suggestive of acute interstitial edematous
pancreatitis
|
None
|
Acute pancreatitis
|
Intravenous hydration, antibiotics and proton pump inhibition and pain
relief.
|
Recovered-Spontaneous labor during hospitalization
|
(2022)26
|
Female
71
|
Hypertension, hyperlipidemia, cerebral infarction
|
Pfizer-BioNTech (mRNA)
|
First
|
2 days
|
Acute upper abdominal pain
Vomiting
|
BP: 142/86 mmHg
HR: 92 beats/min
T: 37.3 °C
|
Lipase:
383 U/L
Amylase: 1043 U/L
|
CT:
diffuse enlargement of the pancreas with ill-defined parenchymal
contours
|
None
|
Acute pancreatitis
|
IV hydration, antibiotics, proton pump inhibition
|
Recovered
|
Alrashdi et al.
(2022)27
|
Female
22
|
None
|
Pfizer-BioNTech (mRNA)
|
First
|
1 week
|
Abdominal pain
Nausea Vomiting Erythematous maculopapular rashes
|
CAO
BP: 118/75 mmHg
HR: 80 beats/min
T: 37 °C
|
WBC: 13 × 109/L
Amylase: 181 U/L
Lipase: 185 U/L
AST: 301 UI/L
ALT: 81 UI/L
|
CT: Edematous pancreas with loss of normal lobulation
|
None
|
Autoimmune pancreatitis acute due to SLE
|
MP, HCQ, AZA
|
Recovered- Discharged at 1 week
|
(2023)28
|
Female
28
|
None
|
BBIBP-CorV (Sinopharm)
|
Second
|
3 months
|
Acute abdominal pain
Nausea
Hemoptysis
Aphagia
Constipation
|
BP: 130/70 mmHg
HR: 101 beats/min
RR: 13 breaths/min
T:37 °C
BMI: 25.7 kg/m2
|
WBC: 8.4 × 109/L
Lipase: 156 U/L
Amyla
se: 1079 U/L
ALT: 80U/L
AST: 44 U/L
TG: 1562 mg/dL
Glycemia: 203 mg/dL
|
CT:
Homogeneous enlargement of the pancreas, extensive peri-pancreatic fat
and peri-pancreatic fluid was observed
|
None
|
Acute pancreatitis
|
Fluid therapy, antibiotics.
|
Recovered
|
Bangolo et al.
(2023)29
|
Male
34
|
None
|
Johnson & Johnson / Jassen vaccine (Viral vector)
|
First
|
1 day
|
Epigastric pain
Nausea Subjective fever
Shivering
|
Tachycardic
Diaphoretic
T: 38.28 °C
|
WBC: 18.9 × 109/L
Lipase:1026 U/L
T-bil: 9.9 mg/dL
ALP: 48 U/L
CRP: 15 mm/h
BUN: 45 mg/dL
Cre: 2.19 mg/dL
|
CT: consistent with acute necrotizing pancreatitis
|
None
|
Acute Pancreatitis
|
Fluid resuscitation (lactated ringer), pain control, and nutritional
support
|
Recovered
|
Stöllberger et al.
(2023)30
|
Female
31
|
Allergic asthma, psoriatic arthritis, neurogenic bladder, and
cholecystolithiasis
|
Pfizer-BioNTech (mRNA)
|
Second
|
2 days
|
Abdominal pain
Nausea
|
None
|
WBC: 12.6 × 109/L
AAE: 418 U/L
Lipase: 1162 U/L
|
CT on the day of admission: necrotizing pancreatitis with enlarged
edematous pancreas.
CT image after 10 days: shows a large acute necrotic collection in the
lesser sac
|
None
|
Pancreatitis
|
EAT with CTX, transgastric drainage
|
Recovered- Discharged at 19 days
|
Ajmera et al.
(2022)15
|
Male
41
|
Bipolar depression, asthma, and obesity
|
Modern (mRNA)
|
Third
|
1 day
|
Abdominal pain
Diarrhea
Sweating Loss appetite
|
BP: 148/100 mm/Hg
HR: 95 beats/min
RR: 18 breaths/min
T: 36.5 °C
SpO2: 100%
BMI: 40 kg/m2
|
WBC: 13.5 × 109/L
Hb: 147 g/L
|
CT: showed acute diverticulitis of the mid-transverse colon, with
adjacent contained micro-perforation
|
None
|
Diverticulitis acute
|
NBM, EAT, intravenous hydration with normal saline
|
Recovered
|
Kyungu et al. (2022)31
|
Male
29
|
None
|
Johnson & Johnson/ Janssen (Viral vector)
|
First
|
2 days
|
Acute abdominal pain
Nausea
Fever
Dark colored urine
|
BP: 153/121 mmHg
HR: 93 beats/min
RR: 20 breaths/min
T: 39.2°C
SpO2: 95%
|
WBC: 2.83 x 109/L
Platelet: 79 x 109/L
AST: 493.9 U/L
ALT: 244.7U/L
GGT: 85U/L
CRP: 148.62 mg/L
|
Ultrasound:
Normal appearing liver (141 mm) without evidence of intrahepatic biliary
dilatation. Wall thickened 7.7 mm without gallstones
|
None
|
Acute acalculous cholecystitis
|
Analgesics, hydration (ringer lactate), antibiotics (cefuroxime
500mg)
|
Recovered- 2 weeks
|
Wahlen et al.
(2022)16
|
Female
52
|
None
|
Pfizer-BioNTech (mRNA)
|
Third
|
8 h
|
Abdominal pain
Shivering Nausea Vomiting Anuria
|
HR: 100 beats/min
T: 38°C
|
WBC :15.8 × 109/L
ANC: 14.6 × 109/L
ALT: 89 U/L
CRP: 10.8 mg/L
|
Ultrasound: Common bile duct was of normal caliber with no intrahepatic
biliary dilatation.
|
None
|
Acalculous cholecystitis
|
Fluid resuscitation, paracetamol, and nutritional support
|
Recovered
|
Vadioaloo et al.
(2022)32
|
Male
72
|
Hypertension, atrial fibrillation with stroke
|
Pfizer-BioNTech (mRNA)
|
First
|
6 hours
|
Colicky abdominal pain
Diarrhea
|
No data
|
Eosinophil count:6.84 x 109/L
|
EGD: showed antral erythematous gastritis
|
Mucosal lymphoplasmacytic cell infiltration with increased
eosinophil
|
Eosinophilic Colitis
|
Any, resolved spontaneously
|
Recovered
|
Cui et al.
(2022)17
|
Female
48
|
None
|
BBIBP-CorV
(Sinopharm)
|
Second
|
1 day
|
Abdominal pain Hematochezia
Fatigue
|
BP: 140/85 mmHg
HR: 80 beats/min
RR: 19 breaths/min
T: 36.2 °C
BMI: 21,1 kg/m 2
|
D-dimer: 329 ug/L
FDP: 2.5 mg/L
Lactic acid:
2.60 mmol/L
|
CT: edema and bowel wall thickening with hypodensity in the sigmoid
colon and descending colon
|
None
|
Ischemic colitis
|
Pinaverium bromide and aspirin enteric-coated tablets
|
Recovered
|