Author contributions
D.Z. had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis. D.Z., H.G., and W.W. conceived and designed the experiment. H.G. performed the analysis with assistance and guidance from Y.L., R.Y. contributed to data quality control of UKB data. H.G., D.Z., and W.W. wrote the manuscript with the participation of all authors.