Crystalline silica-induced recruitment and immuno-imbalance of CD4+ Tissue Resident Memory T cells promote the progression of silicosis.
Yichuan You1, 2#, Xiulin Wu1, 2#, Yangyang He1, 2, Haoyang Yuan1, 2, Yinghui Chen1, 2, Sisi Wang1, 2, Hui Min3, Jie Chen1, 2*, Chao Li1, 2, 4*.
1 Key Laboratory of Environmental Stress and Chronic Disease Control & Prevention (China Medical University), Ministry of Education, No.77 Puhe Road, Shenyang North New Area, Shenyang, 110122, Liaoning, PR China
2 Department of Occupational and Environmental Health, School of Public Health, China Medical University, No.77 Puhe Road, Shenyang North New Area, Shenyang, 110122, Liaoning, PR China
3 Department of Immunology, College of Basic Medical Sciences, China Medical University, No.77 Puhe Road, Shenyang North New Area, Shenyang, 110122, Liaoning, PR China
4 Lead contact.
# These authors contribute equally to this work.
* Corresponding author.
mail: lichao@cmu.edu.cn (C. Li); jchen@cmu.edu.cn (J. Chen)